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In hereditary or acquired metabolic defects, an initial intravenous bolus of 50 mg/kg may be administered over two to three minutes, followed by maintenance doses of 50 mg/kg every six hours or continuous infusion to achieve a total daily exposure of up to 300 mg/kg in critical illness

Its important to remember that everyones weight loss journey is different and shouldnt be compared to someone elses

Recently, the author and his colleagues reported hyperinsulinism prevalence of 75.1% in 684 patients from a general population in New York metropolitan area (ref

In addition, an increased risk of severe depressive episodes and suicidal ideation has been reported during withdrawal phases (63, 64)