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Description

One peptide contains a hydrophobic sequence at its N-terminus (PFVYLI-CAND) 44 , while the other includes a positively charged, hydrophilic HIV-TAT sequence at its N-terminus (CPP-CAND) 45 (Figure

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But, notably, 24 h treatment of NSBSO showed strong cytotoxicity against MCF-7, B16, A549 and 4T1 cells, with IC 50 values of 1.074, 0.844, 1.222 and 4.741 M, respectively, which were much lower than those of reported GSH-responsive peptide derivatives whose IC 50 was greater than 100 M [43]

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Framing non-approved medications as automatically unsafe ignores that all currently approved medications were once non-approved medications working through the same process

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