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In this population, weekly treatment with the glucagon-like peptide 1 (GLP-1) receptor agonist semaglutide leads to both reduced body fat and increased lean body mass, according to a 2021 study presented virtually at the Endocrine Societys annual meeting
Accordingly, a reduced caloric intake has been observed in lean and obese individuals and in patients with T2D after exogenously administered GLP-1 during ad libitum meals
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