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Tchang says
Preclinical studies demonstrated that GLP-1 receptor agonists increased bone formation and reduced bone resorption in metabolic bone disease models, including diabetic osteoporosis, postmenopausal osteoporosis, and glucocorticoid-induced osteoporosis
Immunization of mice with a fragment of -toxin consisting of the C-terminal domain protects them from a lethal myonecrosis infection (Naylor et al., 1999)
Microdosing tirzepatide means starting with doses below standard therapeutic rangestypically 0.5 mg or lowerto evaluate tolerability and metabolic response before advancing to higher maintenance doses
