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In contrast, the longer-acting GLP-1RAs such as liraglutide and semaglutide, engineered for greater resistance to degradation, demonstrate poor penetration into the central nervous system (Salameh et al., 2020)
instead of being a single GLP-1 receptor agonist like semaglutide, tirzepatide is a GLP-1/glucose insulinotropic peptide (GIP) dual agonist, which explains the greater weight loss it delivers
The role of reactive oxygen species (ROS) in the biological activities of metallic nanoparticles
doi: 10.1038/s41580-020-00288-9 Summary Keywords artificial intelligence, combined stresses, flavonoid regulatory networks, genome editing, phenylpropanoid metabolism, predictive metabolic engineering, stress adaptation Citation Hina A, Abbasi A, Chaudhry A, Sanaullah T, Arshad M, Sarwar HM, Sarfaraz S, Karikari B and Kavhiza NJ (2026) A review of flavonoids at the crossroads of plant defense: integrating biotic and abiotic stress tolerance through AI- and CRISPR/Cas-guided metabolic reprogramming
