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Once complexed with Cu(II), the peptide backbone rearranges into a specific square-planar coordination around the copper ion, with donor atoms from the glycine amino terminus, the deprotonated amide nitrogen, the histidine imidazole, and a fourth position (carboxylate or water depending on pH)
Gout, a form of arthritis caused by the buildup of uric acid crystals in the joints, can occasionally affect the wrist and cause sudden, severe pain and swelling
Biomedicines , 9
Naturally produced free-form amino acid from microbial fermentation
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