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These AG-haESCs were cultured in 2i medium consisting of DMEM (Millipore, Billerica, MA, USA) supplemented with 15% FBS (ExCell Bio, Shanghai, China), penicillinstreptomycin, non-essential amino acids, nucleosides, L-glutamine, -mercaptoethanol, 1000 U/mL LIF, 1 M PD0325901 (Selleck Chemicals, Houston, TX, USA), and 3 M CHIR99021 (Selleck Chemicals)

Known for its extensively researched protective and regenerative properties, GHK-Cu has been shown to accelerate wound healing and skin repair by stimulating the synthesis and breakdown of collagen, glycosaminoglycans, and other extracellular matrix components

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We suspected that COVID-19 also might be affecting oxidative stress and glutathione, and in this study we confirmed this in adults hospitalized with COVID-19