For example, emerging protein targets like IL-4, IL-10, IL-15, IL-17, IL-18, IL-23, interleukin-1 receptor-associated kinase (IRAK)-4 have been revealed to have a strong implication with innate and adaptive immune response in RA ( Protein Targets for Treatment of Rheumatoid Arthritis Currently, many agents aiming at various protein targets have been explored and tested to ease the progression of RA, and some agents have been used in the clinic to treat RA patients ( Table 1 )
BPC-157: The Gastric Peptide BPC-157 has been studied in preclinical models for its effects on tissue repair in tendon, ligament, and muscle injury models, protective effects on gastric and intestinal lining, promotion of angiogenesis (new blood vessel formation), and modulation of inflammatory signaling
Frontiers in Aging Neuroscience, 14 , 888292
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