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Itching (Pruritus): Occurs in 5-10% of injection recipients, often at the injection site (e.g., deltoid or gluteal), due to localized histamine release

Consistent with previous findings [3], we observed a significant transient upregulation of glycolytic enzymes such as hexokinase 2 (HK2), phosphofructokinase-1 (PFK-1), pyruvate kinase M2 (PKM2) and lactate dehydrogenase A (LDHA) at 36 h post-injury (Fig