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For chronic weight management, both trizepatide (Zepbound) and semaglutide 2.4 mg (Wegovy) are indicated for adults with a BMI 30 or a BMI 27 with at least one weight-related condition (such as hypertension, dyslipidemia, type 2 diabetes, sleep apnea, or cardiovascular disease)
464,465,466,467,468 These GLP-1 receptor agonists can suppress the inflammatory response of macrophages, thereby inhibiting IR
J Diabetes, Obesity and Metabolism