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1 2 3 Molecular biology of the cell (4th ed.)
At therapeutic doses it is safe for most people, but acetaminophen metabolism uses glutathione directly, and chronic high dose use is the leading cause of acute liver failure in the United States precisely because it exhausts hepatic glutathione (PubMed PMID: 26041729)
Goodman-Gruen D et al
Glutathione plays a crucial role in supporting immune function and possesses potent antioxidant and detoxification properties
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