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Studies have shown that GHK-Cu at concentrations of 0.01, 1, and 100 nM significantly increased the production of elastin and collagen in human dermal fibroblasts, which are the cells responsible for building skin structure
that is the most common early complaint
The rationale for injectable administration stems from the limitations of topical delivery
When the research question specifically isolates these two mechanisms, adding GHK-Cu introduces confounding from its gene-expression and anti-inflammatory effects
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