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And women on GLP-1 medications face a specific nutritional risk profile: reduced iron intake from smaller meal volumes compounding pre-existing deficiency, which is more common in menstruating women to begin with (Urbina et al., 2026, 480,825 adults)
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This feature endows the Trp metabolic axis with potential interventional value in autoimmune-related inflammation, while also indicating that its translational application requires careful evaluation of ligand spectra, receptor context, and tissue specificity
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