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There have been postmarketing reports of renal impairment, acute kidney injury, and worsening of chronic renal failure, which sometimes has required hemodialysis, in patients treated with GLP-1 receptor agonists

Vitamin B12 injections for pernicious anaemia are the gold-standard treatment in the UK, delivering hydroxocobalamin intramuscularly to bypass the absorption problem

Medication Use Certain medications, such as proton pump inhibitors (PPIs) for acid reflux or metformin for diabetes, can interfere with B12 absorption

However, when taken intramuscularly, your body can totally bypass the gastrointestinal system, thereby decreasing the time it takes to reach your body as well as increasing your bodys ability to absorb the vitamin and all its benefits