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While the concept is scientifically sound, it's essential to recognize that most peptides being used clinically have not completed rigorous FDA-approval processes , and much of our understanding comes from preclinical (animal) studies or small, uncontrolled human observations

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Additionally, the same detox and metabolism triggered by the above can also cause a partial histamine breakdown and trapping of methylhistamine which can aggravate all the Sx you mention as well

Pilot study of the effect of methyl B12 treatment on behavioral and biomarker measures in children with autism