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In both cases, oxidative stress is thought to be the common underlying mechanism that leads to cellular dysfunction and, eventual cell death

Beyond the regulatory picture, online forums and peptide communities frequently raise a structural argument about why human trials may never happen: BPC-157s amino acid sequence is in the public domain, which would make it difficult to patent and therefore commercially unattractive for a pharmaceutical company to fund through the expensive late-stage trial process

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This indicates that the overall rates of GSH production from cysteine and methionine and the transport of GSH out of the cell are in the appropriate ranges