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The dark side of GLP-1 receptor agonists primarily revolves around gastrointestinal issues, such as nausea

Factors released by neighbouring -cells or -cells amplify the glucose-induced effects on somatostatin secretion from -cells, which act locally within the islets as paracrine or autocrine inhibitors of insulin, glucagon and somatostatin secretion

314,6008 (1985): 281-3./ Sinha DK, Balasubramanian A, Tatem AJ, Rivera-Mirabal J, Yu J, Kovac J, Pastuszak AW, Lipshultz LI

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