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Integrins affect the microtubule cytoskeleton by promoting microtubule nucleation, growth, and stabilization, whereas microtubules impact integrin function by targeting integrin adhesions to promote their turnover
Approximately one-third of people with psoriasis report being diagnosed before age 20 and affects both sexes equally
It exists naturally in human plasma, saliva, and urine with plasma concentrations averaging ~200 ng/mL at age 20 but declining to ~80 ng/mL by age 60
In addition, the Molecular Signature Database 29 was used to investigate the hallmark gene sets
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