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Carnitine supplementation with 10-50 mg/kg/day significantly reduced symptoms of constipation

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One RCT did not find significant effects of melatonin on the average benzodiazepine dosage, benzodiazepine cessation proportion, or withdrawal symptoms at 24 weeks [100]

(6) M H Rasmussen, J Frystyk, T Andersen, L Breum, et al (1994) The impact of obesity, fat distribution, and energy restriction on insulin-like growth factor-1 (IGF-1), IGF-binding protein-3, insulin, and growth hormone Metabolism, 1994 Mar, Volume 43 (Issue 3), Pages 315-9