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We need to know what lean tissue is lost, its functional efficiency, and the relation to resistance exercises and pharmacological and dietary changes
Consider two people who both lose 15 kilograms on a GLP-1 drug: Lost 15 kg but poorly 10 kg fat lost 5 kg muscle lost Metabolic rate has fallen Blood sugar control worsened Higher fall risk than before Weight regain likely as fat Lost 15 kg and well 14 kg fat lost 1 kg muscle lost (or neutral) Metabolic rate preserved Blood sugar control improved Strength maintained or increased Better long-term weight maintenance Both people lost the same amount of weight by the scale
Polymeric nanofiber leveraged co-delivery of anti-stromal PAK1 inhibitor and paclitaxel enhances therapeutic effects in stroma-rich 3D spheroid models
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