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Autoantibodies and interferon- present in SLE sera enhance binding of the transcriptional repressor CREM to Gpx4 promoter, which leads to suppressed expression of GPX4 and subsequent elevation of lipid-ROS
The SIRT1/HIF2alpha axis drives reductive glutamine metabolism under chronic acidosis and alters tumor response to therapy
Low-normal or borderline B12 levels combined with elevated MMA may indicate functional B12 deficiency even before overt symptoms appear
Calcitonin and amylin receptor peptide interaction mechanisms: insights into peptide-binding modes and allosteric modulation of the calcitonin receptor by receptor activity-modifying proteins
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