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That one was not negative there was no increased risk, which was why the FDA demanded these tests but there was also no benefit
The dose-escalation schedule reduced early GI events
Diabetes Care 28(5):10921100 DeFronzo RA, Okerson T, Viswanathan P, Guan X, Holcombe JH, MacConell L (2008) Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: a randomized, cross-over study
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