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The immunopathology of sepsis and potential therapeutic targets
SGLT2 inhibition reduces glucose reabsorption at the level of the proximal renal tubule, promotes urinary glucose excretion independent of insulin action, and causes a negative caloric balance ( Figure 1 )
Dosing increases gradually: Treatment begins with a low dose and steps up slowly so the body has time to adjust
Oxidative stress associated DNA damage in testis of mice: induction of abnormal sperms and effects on fertility
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