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In graft kidney injury models, lactate released from ischemia-reperfusion-injured tubular cells can transmit a ferroptosis-permissive state to neighboring cells through metabolic shuttling

Glutathione: A well-known brightening ingredient that helps reduce the look of dullness and discoloration for a clearer, more even appearance

By directly quenching these free radicals, glutathione helps prevent them from stealing electrons from healthy cellular structures, thereby helping to halt the chain reaction of oxidative damage that leads to cellular exhaustion and tissue degradation

Plant-derived inhibitors obtusilactone A and sesamin effectively block LONP1 proteolytic function by forming hydrogen-bond networks with serine 855 and lysine 898 residues in its active site, thereby inducing apoptosis in lung cancer cells [141]