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In THP-1-derived macrophages, Lca dramatically increased the expression of PPAR, LXR, and ABCA1 upon LPS challenge, which was consistent with the findings that activation of the PPAR-LXR-ABCA1 pathway achieved an anti-inflammatory effect, and ligands of PPARs caused a substantial reduction of experimental ALI ( 23 , 24 )

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Assay: Glutathione in yeast media

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Bayer: C,L

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GIP, gastric inhibitory polypeptide

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