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Sphingosine, considered the backbone of sphingolipids, is a key component of cell membranes, and involved in cell signaling, membrane structure, and are associated with cell-growth arrest and the induction of cell death 92,93

A model of redox kinetics implicates the thiol proteome in cellular hydrogen peroxide responses

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After feeding all branching pathways, the excess of glycolytic flux is converted to lactate to preserve a sufficient pool of NAD+ for glycolysis and also to avoid the tricarboxylic acid (TCA) cycle inhibition due to excess NADH