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These patches can contain compounds like: green tea extract bitter orange pyruvate herbal extracts The idea is that ingredients bypass the digestive system and enter the bloodstream directly, making them potentially faster-acting and easier to absorb than oral supplements

Starting with the discovery that glucagon-like peptide 1 (GLP-1) regulates amphetamine-induced locomotion, 1 GLP-1 receptor (GLP-1R) agonism has been shown to reduce the rewarding properties of cocaine and other drugs of abuse in rodents

That synthetic nonapeptide is the molecule sold here

This inhibition preserves nicotinamide availability for the NAD+ salvage pathway, the primary route for NAD+ regeneration in mammalian cells