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Penicillamine, a copper chelator used in Wilson disease, requires dose adjustment in hepatic impairment precisely because liver function determines the rate at which mobilized copper can be processed and excreted [10]

Probiotic treatment improves post-traumatic stress disorder outcomes in mice

There are no randomised controlled trials supporting their use in this condition, and patients should continue evidence-based therapies such as disease-modifying antirheumatic drugs (DMARDs) as recommended by NICE guidance