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Sci Rep 12(1):6666 Liu C, Li C, Cai X, Zou Y, Mo J, Chen B, Cai Y, Han T, Huang W, Qian H, Zhang W (2021) Discovery of a novel GLP-1/GIP dual receptor agonist CY-5 as long-acting hypoglycemic, anti-obesity agent

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Initial calorie prescription was 75% of the basal energy expenditure for age

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These peptides boost the release of GLP-1 from intestinal cells, increasing feelings of fullness

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TABLE 1 Summary of the mechanisms of action and effects of GLP-1R agonists in AD

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