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565 The disturbance of iron homeostasis in the brain and ferroptosis of neurons can exacerbate neuroinflammation, causing abnormal microglial activation
To further elucidate the therapeutic mechanisms underlying D-CuPs multivalent interactions, comprehensive proteomic analysis revealed two pivotal transcriptional regulators, the tumor suppressor protein p53 and histone deacetylase 7 (HDAC7) to be potential mechanistic targets
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Fragaki G, Stefanaki I, Dais P, Mikros E
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