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According to the 2024 American Diabetes Association Standards of Care, GLP-1 receptor agonists have become first line pharmacotherapy for most patients with type 2 diabetes mellitus (T2DM), including those with concomitant atherosclerotic cardiovascular disease (ASCVD), indicators of high ASCVD risk, or chronic kidney disease
Doing it wrong can cause bruising, bleeding, or even infection
However, it is currently classified in Group B of the AIS, which means that benefits are possible but the evidence remains insufficient or contradictory
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J Neurochem 92(4):798806 Ambery P, Parker VE, Stumvoll M, Posch MG, Heise T, Plum-Moerschel L et al (2018) MEDI0382, a GLP-1 and glucagon receptor dual agonist, in obese or overweight patients with type 2 diabetes: a randomised, controlled, double-blind, ascending dose and phase 2a study
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