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However, post-marketing surveillance and patient reports suggest that some individuals taking semaglutide do experience leg cramps during treatment

The starting dose guide covers initial dosing considerations in detail

U., Caruso, U., Cravotto, E., D'Iddio, S., Corsi, M., Pola, P., Savi, L., and Grilli, M

17 Therefore, physicians and pharmacists are encouraged to advise their patients taking exenatide to be aware of the signs and symptoms of acute pancreatitis and to seek prompt medical attention should they experience unexplained, persistent, severe abdominal pain, which may be accompanied by nausea, vomiting, and fever