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For example, owing to their conformational flexibility, IDRs have a high propensity to undergo posttranslational modifications, such as acetylation, glycosylation, methylation, or phosphorylation 15,17
When weight is lost quickly, the liver secretes extra cholesterol into bile, and reduced gallbladder motilitypartly due to the drug's effect on gastric emptyingcan lead to bile stasis
doi: 10.1016/j.neuropharm.2013.08.005 74 McCleanPLParthsarathyVFaivreEHolscherC
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