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Among these candidates, TRIM28 ranked second and was prioritized because of its known role in heterochromatin maintenance and repression of differentiation genes, 36,37 although its early embryonic lethality prevented its inclusion in the initial screening
IV therapy is not suitable for individuals with certain medical conditions such as kidney disease, heart failure, or known allergies to any of the ingredients
Further understanding of the role of epigenetics in human aging and longevity requires a deeper understanding of the influence of the external environment on epigenetics, such as the mechanism of epigenetics in CR-mediated longevity regulation
PLoS One 10(3):e0121060
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