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This pharmacological profile creates a dose-dependent weight loss curve that, in clinical trials, reached 24.2% at the 12mg weekly dose over 48 weeks and an astonishing 28.7% at 12mg over 68 weeks in the TRIUMPH-4 phase 3 trial

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13-16 weeks : After assessment, your doctor will escalate the dosage to 8 mg once weekly for the next 4 weeks 17-21 weeks : If your body tolerates 8 mg for 4 weeks, your doctor will increase the dose to 12 mg once weekly onwards

If PhRMA lobbies hard enough and they're able to get this done, like what they want to do, reclassifying all these as biologics, it allows them to extend the patent for 10 to 12 years