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In determining the source of shares to close out the covered short position, the underwriters will consider, among other things, the price of shares available for purchase in the open market as compared to the price at which they may purchase shares through the option to purchase additional shares granted to them under the underwriting agreement described above

Because of its presence in blood and tissue fluids, it is considered a physiologic carrier of copper, with roles in signaling and tissue maintenance that remain under active investigation

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