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Protecting RGCs effectively requires targeted inhibition of cell death signaling and/or enhancement of survival signaling without compromising TNF--triggered survival pathways (164)

People with Type 2 diabetes have many medication options to manage the disease

Considering duplicate or implausible reports can lead to significant errors [22], extensive cleaning, and normalization were conducted to ensure interpretable data (detailed process is provided in Additional file 1: Fig S1[23,24,25])

To better understand biofilm development and persistence in chronic wounds, Figure 2 illustrates the stages of the biofilm life cycle, including adhesion, microcolony formation, maturation, and dispersion, as well as host immune responses such as neutrophil recruitment, M1/M2 macrophage polarization, and cytokine signaling (e.g., interleukin-1 beta [IL-1], tumor necrosis factor-alpha [TNF-], interleukin-6 [IL-6], interleukin-8 [IL-8], interleukin-12 [IL-12]), which collectively contribute to immune evasion and chronic infection [40-43]