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One small nondiabetic study showed a 6.5% weight loss with sitagliptin versus 7.65% with metformin, but larger studies in T2DM have not confirmed a direct effect on weight
GLP-1 medications reduce inflammation and improve metabolic health, which can decrease chronic immune activation, one of the major drivers of accelerated aging in people with HIV
[PMID: 9056994] PubMed record related to this compound for laboratory literature review
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