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At present, several studies have found that GLP-1 analog Lira may improve lipid metabolism and fat deposition by downregulating the expression of lipid metabolism-related genes FAS, and ACC-a mRNA, or promoting the expression of PI3K protein in mouse liver

Due to their potential to improve mortality and morbidity outcomes, GLP-1 drugs are becoming an increasingly salient topic for insurers, particularly in relation to mortality improvement, medical underwriting, and new product development