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Side effects were mainly mild-to moderate gastro-intestinal symptoms (nausea, vomiting, diarrhoea) mostly occurring with higher doses of retatrutide and with faster titration (Table 2)
Monotherapy with RYBELSUS 7 mg and RYBELSUS 14 mg once daily for 26 weeks resulted in a statistically significant reduction in HbA1c compared with placebo (see Table 4)
Semaglutide is primarily an appetite suppressant, dissuading the consumption of excessive calories, which are eventually stored as body fat
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