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This outperformance of an established clinical therapy suggests significant potential for diabetic wound applications

Market growth is driven by rising chronic disease prevalence, advancements in targeted therapeutics, and increased investment in drug discovery

The increase in its levels in low ESR patients, points to a potential ongoing systemic inflammation, increased transcriptional activity and histone acetylation/methylation dynamics, activating an epigenetic activation/turnover signature in RA (Teitsma et al., 2018

4,6,13 Concurrent hormone replacement therapy (HRT) potentiates this effect by restoring the protective estrogenic milieu