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The New England Journal of Medicine , 373 (1), 1122
CRISPR-Cas9 in vivo gene editing for transthyretin amyloidosis
How much risk remains hotly debated
Indeed, in a 2021 publication, the authors state that:20 NAD has already been implicated in various cancers, as cancer requires vast energy to proliferate High levels of NAD bestow therapy resistance to cancers Higher levels of NAD may cause tumors to be more potent And starving cancer of NAD and from the enzymes found in the myriad of NAD pathways may also hold merit in the fight against slowing further cancer progression At the same time, other research has posited that higher NAD+ levels have an inverse relationship with cancer, with a 2023 study in particular finding that NAD [supplementation] suppresses tumor metastasis.21 So, whats the verdict does NAD+ boosting prevent cancer or promote it
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