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Archived from the original on 16 January 2017
Different bioavailability characteristics
In addition to limited absorption via the IF, the intake of high-dose supplements leads to passive diffusion, i.e., the vitamin can freely enter the bloodstream without IF binding and receptor uptake
The elderly who have diets with limited animal-sourced foods are vulnerable populations for that reason and also because intestinal absorption declines with age, a consequence of low stomach acid
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