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The charged nature of GSH (negative at physiological pH) suggests that GSH cannot passively diffuse into the mitochondria, because the mitochondrial matrix has a negative potential relative to the cytoplasm
Because liposomes can fuse with cell membranes, they allow for more direct and efficient delivery of their cargo into cells - making liposomal supplements highly effective
doi:10.1097/gme.0b013e3181f2f01a 59
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