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Polyphenols selectively reverse early-life stress-induced behavioural, neurochemical and microbiota changes in the rat
These may include improvements in blood pressure, lipid profiles, and markers of inflammation
They imitate a naturally occurring hormone in the gut called GLP-1, which helps regulate blood sugar levels by increasing insulin production in response to food intake
Tamoxifen isnt something we typically use to treat mania, but it was an investigational compound, really based on its mechanism of action as a protein kinase C inhibitor
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