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Another study shows that TMAO suppresses Nrf2 and its downstream antioxidant response elements, leading to increased intracellular ROS generation and reduced SOD activity (Luo et al., 2024)
Also, keep in mind that folic acid supplements may interact with commonly prescribed medications, including methotrexate, sulfasalazine, and various anti-epileptic medications such as Depacon, Dilantin, and Carbatrol ( As such, if you take any of these medications, consult your healthcare provider before taking folic acid supplements, regardless of their strength
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Furthermore, DMSO readily crosses most tissue membranes of lower animals and man 9
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