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For comparisons between two groups, normally distributed data with equal variances were analyzed using a two-tailed unpaired Students t-test, while non-normally distributed data or data with unequal variances were assessed using the Mann-Whitney U test
No statistically significant increases in chromosomal aberrations were observed in CHO cells at any tested concentration
10.1038/nrm3311 29 HarhayG
The limited efficacy of even potent immunosuppression in the later stages (Wolinsky et al., 2020) is likely due to a waning of the acute/adaptive auto-immune component, rather than restricted access of biologicals to the CNS (as an example of adequate access of biologicals to the brain, systemic administration of anti-amyloid antibodies in Alzheimers has now been shown to be effective at reducing amyloid load (Jucker and Walker, 2023
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