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NET has a definite role in controlling infection, but increasingly more studies have shown that excessive production of NET can cause thrombosis and tissue damage (182, 183, 185)

Aside from direct membrane attack, other mechanisms for amyloid antimicrobial activities include the induction of protein aggregation within the bacteria itself leading to death, conformational changes to microbial proteins by amyloid binding, thereby inhibiting their function or agglutination of microbes into large aggregates (Chen et al., 2022)

The Chinese experience of male infertility