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According to a meta-analysis of 11 clinical trials (791 patients), ALCAR is superior to placebo in reducing depressive symptoms
Moreover, clinical data from 17 patients suggested that early monitoring of TSH after starting tirzepatide might be necessary to avoid iatrogenic hyperthyroidism in patients with hypothyroidism 68
Therefore, therapeutic options that could work in a way other than classic antidepressants are being sought to increase the effectiveness of the treatment
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