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4.3 GLP-1RAs and colorectal cancer He Wenjing (75) reported that GLP-1R expression was lacking in human colon cancer tissues and colon cancer cell lines

Its about giving patients their agency back

In the drugs best showing so far, the ATTAIN-1 trial, people taking orforglipron lost on average 12.4% of their baseline weight, a notch below the roughly 14% weight loss seen in similar trials of Novo Nordisks injectable Wegovy and also below the typical results seen with Eli Lillys tirzepatide, a dual GLP-1/GIP medication

Lifestyle changes, such as treating mood issues and seeking sleep support, can also make a difference, as can solo or couples therapy to tackle relationship problems